6.88 % | ARK Investment Management LLC | 12,983,002 | 288,777 | 30.9.2023 |
6.68 % | Casdin Capital, LLC | 12,604,275 | -3,430 | 30.6.2023 |
5.49 % | Novartis AG | 10,367,340 | 0 | 10.4.2023 |
5.02 % | BlackRock Institutional Trust Company, N.A. | 9,472,149 | 243,527 | 30.6.2023 |
4.63 % | Nikko Asset Management Co., Ltd. | 8,741,437 | 4,411,248 | 30.6.2023 |
4.14 % | The Vanguard Group, Inc. | 7,807,350 | 102,342 | 30.6.2023 |
3.96 % | Madryn Asset Management, LP | 7,469,202 | 0 | 30.6.2023 |
2.76 % | Tikvah Management LLC | 5,215,740 | 1,001,000 | 30.6.2023 |
2.76 % | Millennium Management LLC | 5,199,020 | -621,917 | 30.6.2023 |
2.60 % | Point72 Asset Management, L.P. | 4,906,490 | 45,427 | 30.6.2023 |
1.92 % | Gold (Larry) | 3,627,197 | -5,505,869 | 31.12.2022 |
1.80 % | Foresite Capital Management, LLC | 3,403,276 | -113,196 | 30.6.2023 |
1.66 % | Geode Capital Management, L.L.C. | 3,131,743 | 107,899 | 30.6.2023 |
1.56 % | State Street Global Advisors (US) | 2,952,331 | 40,876 | 30.6.2023 |
1.36 % | Marshall Wace LLP | 2,559,708 | 0 | 30.6.2023 |
1.35 % | Barclays Bank PLC | 2,548,174 | -20,928 | 30.6.2023 |
1.17 % | Magnetar Capital Partners LP | 2,199,292 | -100,725 | 30.6.2023 |
0.99 % | Redmile Group, LLC | 1,870,839 | 0 | 30.6.2023 |
0.90 % | Nan Fung Group Holdings Ltd | 1,696,558 | 0 | 30.6.2023 |
0.79 % | Perceptive Advisors LLC | 1,500,000 | 0 | 30.6.2023 |
0.71 % | Morgan Stanley Investment Management Inc. (US) | 1,333,804 | 151,807 | 30.6.2023 |
0.64 % | Northern Trust Investments, Inc. | 1,201,587 | 1,406 | 30.6.2023 |
0.62 % | Charles Schwab Investment Management, Inc. | 1,160,653 | 33,947 | 30.6.2023 |
0.52 % | Nikko Asset Management Americas, Inc. | 984,457 | 273,530 | 31.12.2022 |
0.46 % | Zweig-DiMenna Associates, Inc. | 868,218 | -400,000 | 30.6.2023 |
0.43 % | Gagnon Securities LLC | 805,337 | -26,764 | 30.6.2023 |
0.42 % | Monashee Investment Management, LLC | 799,784 | -190,077 | 30.6.2023 |
0.41 % | BlackRock Financial Management, Inc. | 775,403 | -9,176 | 30.6.2023 |
0.40 % | Goldman Sachs & Company, Inc. | 754,599 | 137,291 | 30.6.2023 |
0.33 % | Dimensional Fund Advisors, L.P. | 617,509 | 537,524 | 30.6.2023 |
0.32 % | Gagnon Advisors, LLC | 605,671 | 92,703 | 30.6.2023 |
0.25 % | Driehaus Capital Management, LLC | 467,856 | 0 | 30.6.2023 |
0.24 % | Voya Investments, LLC | 456,455 | 0 | 30.4.2023 |
0.24 % | General American Investors Company, Inc. | 450,000 | 0 | 30.6.2023 |
0.23 % | Parametric Portfolio Associates LLC | 437,917 | 8,577 | 30.6.2023 |
0.23 % | Saba Capital Management, L.P. | 437,676 | -18,779 | 30.6.2023 |
0.23 % | BlackRock Investment Management, LLC | 437,611 | 24,438 | 30.6.2023 |
0.23 % | Quake (Stephen Ph.D.) | 425,000 | 0 | 10.4.2023 |
0.22 % | BofA Global Research (US) | 416,401 | -78,695 | 30.6.2023 |
0.22 % | Nuveen LLC | 414,633 | 0 | 30.6.2023 |
0.21 % | RBF Capital, LLC | 400,000 | -116,018 | 30.6.2023 |
0.21 % | Lillis (Charles M) | 396,576 | 3,430 | 10.4.2023 |
0.21 % | BNY Mellon Asset Management | 394,351 | -9,461 | 30.6.2023 |
0.18 % | Schweizerische Nationalbank | 347,700 | 44,200 | 30.6.2023 |
0.17 % | Intellectus Partners, LLC | 325,000 | 0 | 30.6.2023 |
0.15 % | Johnson & Johnson Innovation-JJDC, Inc. | 281,052 | 0 | 30.6.2023 |
0.14 % | Boothbay Fund Management, LLC | 273,422 | -11,741 | 30.6.2023 |
0.13 % | Northern Trust Global Investments | 248,927 | 132,684 | 30.6.2023 |
0.13 % | Cowen & Co., LLC | 247,226 | 0 | 30.6.2023 |
0.12 % | Rhumbline Advisers Ltd. Partnership | 231,258 | -7,027 | 30.6.2023 |
0.11 % | JP Morgan Asset Management | 213,109 | 18,252 | 30.6.2023 |
0.10 % | Morgan Stanley & Co. LLC | 193,203 | -4,078 | 30.6.2023 |
0.10 % | AllianceBernstein L.P. | 191,320 | 32,820 | 30.6.2023 |
0.10 % | California State Teachers Retirement System | 190,758 | 9,942 | 30.6.2023 |
0.10 % | Connor, Clark & Lunn Investment Management Ltd. | 183,520 | -128,143 | 30.6.2023 |
0.09 % | BlackRock Investment Management (UK) Ltd. | 172,756 | 0 | 30.6.2023 |
0.09 % | UBS Asset Management (Switzerland) | 171,701 | 0 | 31.3.2023 |
0.09 % | Invesco Capital Management LLC | 170,048 | -1,819 | 30.6.2023 |
0.07 % | Oak Family Advisors, LLC | 133,296 | -21,033 | 30.9.2023 |
0.07 % | Kent Lake Capital LLC | 129,995 | 129,995 | 30.6.2023 |
0.07 % | Mellon Investments Corporation | 126,235 | -16,638 | 30.6.2023 |
0.07 % | Legal & General Investment Management Ltd. | 122,907 | 67,185 | 30.6.2023 |
0.06 % | UBS Financial Services, Inc. | 117,546 | 45,899 | 30.6.2023 |
0.06 % | D. E. Shaw & Co., L.P. | 113,248 | -93,859 | 30.6.2023 |
0.06 % | Credit Suisse Funds AG | 112,857 | 8,333 | 30.6.2023 |
0.06 % | Tamarack Advisers, LP | 110,000 | -365,000 | 30.6.2023 |
0.05 % | Commonwealth Financial Network | 100,500 | 500 | 30.6.2023 |
0.05 % | Edgewood Management LLC | 100,000 | 0 | 30.6.2023 |
0.05 % | Post (Richard A) | 97,430 | 40,000 | 10.4.2023 |
0.05 % | Susquehanna International Group, LLP | 95,727 | -34,672 | 30.6.2023 |
0.05 % | Inspire Advisors, LLC | 91,969 | 91,969 | 30.6.2023 |
0.05 % | Abaris Investment Management AG | 91,000 | -60,000 | 30.4.2023 |
0.05 % | Towercrest Capital Management, LLC | 90,575 | 90,575 | 30.6.2023 |
0.05 % | BlackRock Advisors (UK) Limited | 86,907 | -259 | 30.9.2023 |
0.05 % | Avantis Investors | 86,292 | 32,909 | 30.9.2023 |
0.04 % | MetLife Investment Management, LLC | 83,329 | 0 | 30.6.2023 |
0.04 % | T. Rowe Price International Ltd | 79,285 | 1,362 | 30.6.2023 |
0.04 % | Cox (Troy M) | 78,430 | -25,070 | 10.4.2023 |
0.04 % | DWS Investments UK Limited | 78,019 | -19,290 | 30.6.2023 |
0.04 % | Jump Financial, LLC | 76,690 | 76,690 | 30.6.2023 |
0.04 % | American Century Investment Management, Inc. | 75,956 | 42,025 | 30.6.2023 |
0.04 % | Goldman Sachs Asset Management, L.P. | 73,296 | -15,036 | 30.6.2023 |
0.04 % | SunAmerica Asset Management, LLC | 72,749 | -1,584 | 30.6.2023 |
0.04 % | SG Americas Securities, L.L.C. | 69,212 | 55,626 | 30.9.2023 |
0.04 % | Citadel Advisors LLC | 68,673 | -57,560 | 30.6.2023 |
0.04 % | BlackRock Asset Management Ireland Limited | 67,311 | 4,604 | 30.6.2023 |
0.03 % | Lauxera Capital Partners | 65,000 | 0 | 31.8.2023 |
0.03 % | Hightower Advisors, LLC | 64,984 | 1,482 | 30.6.2023 |
0.03 % | Manulife Investment Management (North America) Limited | 64,962 | 4,117 | 30.6.2023 |
0.03 % | Janus Henderson Investors | 64,509 | -1,673,305 | 30.6.2023 |
0.03 % | Caspar Asset Management S.A. | 64,000 | 9,000 | 31.12.2022 |
0.03 % | Vaughan Nelson Investment Management, L.P. | 63,998 | 22,936 | 30.6.2023 |
0.03 % | Public Employees' Retirement Association of CO | 63,118 | 0 | 30.6.2023 |
0.03 % | Emerge Canada Inc | 62,683 | 0 | 31.8.2023 |
0.03 % | Voya Investment Management LLC | 59,960 | 4,481 | 30.6.2023 |
0.03 % | Dimensional Fund Advisors, Ltd. | 59,681 | 0 | 31.8.2023 |
0.03 % | Royce Investment Partners | 59,470 | 6,370 | 30.6.2023 |
0.03 % | Wells Fargo Bank, N.A. | 57,606 | 29,922 | 30.6.2023 |
0.03 % | Corient Private Wealth LLC | 55,000 | 55,000 | 30.6.2023 |
0.03 % | Rice Hall James & Associates, LLC | 50,714 | -1,516 | 31.1.2022 |